Anti-SATB1 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-SATB1 Rabbit Polyclonal Antibody

Anti-SATB1 Rabbit Polyclonal Antibody

Anti-SATB1 Rabbit Polyclonal Antibody

Anti-SATB1 Rabbit Polyclonal Antibody

15400-1-AP-150UL

10094-154EA 462.47 USD

10094-154

Anti-SATB1 Rabbit Polyclonal Antibody

Antibodies

Epigenetic modifications and dynamic changes in chromatin organization by organizer proteins have recently been shown to play an instrumental role in regulating cancer-promoting genes. Special AT-rich binding protein (SATB1) is a unique type of global regulator that integrates higher-order chromatin organization -withregulation of gene expression. SATB1 is a T cell-enriched transcription factor and a chromatin organizer essential for controlling genes that participate in T-cell development and activation. It regulates gene expression by periodically anchoring matrix attachment regions to the nuclear matrix and directly recruiting chromatin-modifying factors. Depending on its posttranslational modifications, SATB1 activates or represses multiple genes.Its expression is regulated by interleukin-4 (IL4) during T helper-2(Th2) cell differentiation.

Western Blot: Human Brain Tissue, 1:1000-1:10000

Type: Primary
Antigen: SATB1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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