Anti-SAMHD1 Rabbit Polyclonal Antibody

Supplier: Proteintech
12586-1-AP-150UL
10094-128EA 462.47 USD
10094-128
Anti-SAMHD1 Rabbit Polyclonal Antibody
Antibodies
SAMHD1, highly expressed by monocytes and monocyte-derived dendritic cells and by monocyte-derived macrophages at a lower extent, is reported as an HIV-1 restriction factor that inhibits the early step of the HIV-1 life cycle. Vpx (virus-like particles containing viral protein X) could overcome this block by interacting with SAMHD1, inducing proteasome-dependent degradation of SAMHD1. Mutations in SAMHD1 cause Aicardi-Goutières syndrome, a genetic encephalopathy with a presumed immune pathogenesis. This antibody 12586-1-AP is raised againt N-terminal 314 amino acids of the full length SAMHD1.

Western Blot: HepG2 Cells, 1:500-1:5000; IHC: Human lung cancer Tissue, 1:20-1:200; IP:K-562 Cells, 1:200-1:1000

Type: Primary
Antigen: SAMHD1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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