Anti-HEXIM1 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-HEXIM1 Rabbit Polyclonal Antibody

Anti-HEXIM1 Rabbit Polyclonal Antibody

Anti-HEXIM1 Rabbit Polyclonal Antibody

Anti-HEXIM1 Rabbit Polyclonal Antibody

Anti-HEXIM1 Rabbit Polyclonal Antibody

Anti-HEXIM1 Rabbit Polyclonal Antibody

Anti-HEXIM1 Rabbit Polyclonal Antibody

Anti-HEXIM1 Rabbit Polyclonal Antibody

15676-1-AP-150UL

10087-290EA 462.47 USD

10087-290

Anti-HEXIM1 Rabbit Polyclonal Antibody

Antibodies

HEXIM1, also named CLP1, EDG1, HIS1 or MAQ1, is best known as the inhibitor of positive transcription elongation factor b, which regulates the transcription elongation of RNA polymerase II and controls 60-70% of mRNA synthesis. HEXIM1 regulates NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Previous studies showed that HEXIM1 interacts with two key p53 regulators, nucleophosmin and HDM2, implying a possible connection between HEXIM1 and the p53 signaling pathway. For this antibody, western blotting analysis always appears a 70-kDa band which is consistent with that in a previous finding with a currently unknown reason.

Western Blot: HeLa Cells, 1:200-1:2000; IHC: Human breast cancer Tissue, 1:20-1:200; IF: MCF-7 Cells, 1:10-1:100; IP: MCF-7 Cells, 1:200-1:2000

Type: Primary
Antigen: HEXIM1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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