Anti-Fibrinogen beta chain Rabbit Polyclonal Antibody

Supplier: Proteintech
16747-1-AP-150UL
10086-958EA 462.47 USD
10086-958
Anti-Fibrinogen beta chain Rabbit Polyclonal Antibody
Antibodies
Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia . FGB is the beta chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide B is cleaved from FGB by thrombin. Mutations in the gene of FGB lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Western Blot: Mouse Heart Tissue, 1:500-1:5000; IHC: Human Kidney Tissue, 1:20-1:200

Type: Primary
Antigen: Fibrinogen beta chain
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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