Anti-FAS Mouse Monoclonal Antibody [clone: 1G7F7]

Supplier: Proteintech
60196-1-IG-150UL
10086-872EA 462.47 USD
10086-872
Anti-FAS Mouse Monoclonal Antibody [clone: 1G7F7]
Antibodies
FAS, also named as CD95, APO-1, APT1, FAS1 and TNFRSF6, is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily, can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.

Western Blot: MCF7 Cells, 1:200-1:1000

Type: Primary
Antigen: FAS/CD95
Clonality: Monoclonal
Clone: 1G7F7
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse
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