Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Supplier: Proteintech

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

66099-1-IG-150UL

10086-714EA 462.47 USD

10086-714

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Antibodies

In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snoRNA and snRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs . EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and involves in a multitude of cellular RNA processing and degradation events .

Western Blot:Jurkat Cells, 1:500-1:5000; IF: HepG2 Cells, 1:10-1:100; IHC: Human Liver Tissue, 1:20-1:200

Type: Primary
Antigen: EXOSC2
Clonality: Monoclonal
Clone: 1G8B1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human

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