Anti-EIF5B Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-EIF5B Rabbit Polyclonal Antibody

Anti-EIF5B Rabbit Polyclonal Antibody

Anti-EIF5B Rabbit Polyclonal Antibody

Anti-EIF5B Rabbit Polyclonal Antibody

Anti-EIF5B Rabbit Polyclonal Antibody

Anti-EIF5B Rabbit Polyclonal Antibody

13527-1-AP-150UL

10086-456EA 462.47 USD

10086-456

Anti-EIF5B Rabbit Polyclonal Antibody

Antibodies

Translation initiation requires the delivery of the initiator methionine tRNA to the 40S ribosomal subunit. The initiator methionine tRNA is delivered by the heterotrimeric complex EIF2 in a ternary complex with GTP that interacts with the 40S subunit. The resulting complex then binds to an mRNA and scans for the AUG start codon. Eukaryotic translation initiation factor 5B (EIF5B) plays a role in recognition of the AUG codon in conjunction with translation factor eIF2, which functions to general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes, and promotes joining of the 60S ribosomal subunit.

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human gliomas, 1:20-1:200; IF: MCF-7, 1:20-1:200

Type: Primary
Antigen: EIF5B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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