Anti-CHK2 Rabbit Polyclonal Antibody

Supplier: Proteintech
13954-1-AP-150UL
10084-710EA 462.47 USD
10084-710
Anti-CHK2 Rabbit Polyclonal Antibody
Antibodies
Chk2(Checkpoint kinase 2) is also named as CDS1, CHEK2, RAD53 and belongs to the CHK2 subfamily. It is a protein kinase that is activated in response to DNA damage and involved in cell cycle arrest. It also mediates the induction of senescence in fibroblasts, but is dispensable for the induction of telomere dysfunction checkpoints at the stem and progenitor cell level. This protein can exsit as a dimer . Active forms of CHEK2 devoid of phosphorylation at Thr-68 can form unstable dimers. Defects in CHEK2 is a cause of susceptibility to breast cancer (BC). It has 12 isoforms produced by alternative splicing.

Western Blot:Jurkat Cells, 1:200-1:2000

Type: Primary
Antigen: CHK2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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