Anti-DDX58 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-DDX58 Rabbit Polyclonal Antibody

Anti-DDX58 Rabbit Polyclonal Antibody

Anti-DDX58 Rabbit Polyclonal Antibody

Anti-DDX58 Rabbit Polyclonal Antibody

Anti-DDX58 Rabbit Polyclonal Antibody

Anti-DDX58 Rabbit Polyclonal Antibody

Anti-DDX58 Rabbit Polyclonal Antibody

Anti-DDX58 Rabbit Polyclonal Antibody

25068-1-AP-150UL

10081-720EA 462.47 USD

10081-720

Anti-DDX58 Rabbit Polyclonal Antibody

Antibodies

DDX58, also named as RIG-1, belongs to the helicase family. It is involved in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). It is essential for the production of interferons in response to RNA viruses including paramyxoviruses, influenza viruses, Japanese encephalitis virus and HCV.

Western Blot:A431 Cells, 1:200-1:2000; IHC: Human Heart Tissue, 1:20-1:200

Type: Primary
Antigen: DDX58
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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