Anti-PARP1 Rabbit Polyclonal Antibody

Supplier: Proteintech
13371-1-AP-150UL
10081-700EA 462.47 USD
10081-700
Anti-PARP1 Rabbit Polyclonal Antibody
Antibodies
PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis. In addition to caspases, other proteases like calpains, cathepsins, granzymes and matrix metalloproteinases (MMPs) have also beenMore Product Information
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