Anti-TBP Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-TBP Rabbit Polyclonal Antibody

Anti-TBP Rabbit Polyclonal Antibody

22006-1-AP-150UL

10081-148EA 462.47 USD

10081-148

Anti-TBP Rabbit Polyclonal Antibody

Antibodies

The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody recognize human TBP with MW 40 kDa and mouse/rat Tbp with MW 34 kDa.

Western Blot:COLO 320 Cells, 1:500-1:5000

Type: Primary
Antigen: TBP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse

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