Anti-TNFRSF10D Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences
ADI-AAP-371-E
10049-816EA 539.55 USD
10049-816
Anti-TNFRSF10D Rabbit Polyclonal Antibody
Antibodies
Decoy receptors (DcRs) are signaling-deficient receptors for certain members of the TNF family of cytokines, including TRAIL/Apo2L and FasL. Functional TRAIL receptors such as DR4 and DR5 transmit apoptotic signals via their intracellular death domains. In contrast, three identified TRAIL decoy receptors (DcR1, DcR2, and osteoprotegerin/OPG) completely or partially lack the signaling death domain, and/or are secreted from cells and unable to transmit intracellular signals. Thus, expression of DcRs promotes survival by sequestration of apoptotic ligands. A fourth identified decoy receptor, DcR3, binds both FasL and the vascular endothelial cell growth inhibitor (VEGI), inhibiting Fas and DR3 death signals.

Type: Primary
Antigen: TNFRSF10D
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat
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